Abstract：Using raw diatomite and calcined diatomite as carrier, the diatomite based antibacterial inorganic material was obtained by adsorption method to load the cpf antibacterial agent of 20×16-6 on diatomite. The properties of different diatomite carriers were investigated by SEM and BET. Moreover, the antibacterial performance of the ciprofloxacin/diatomite inorganic material was studied. Results show that the adsorption property of the diatomite on ciprofloxacin is very well. The loading rate of raw diatomite can amount to 60.79% and the calcined diatomite can amount to 24.78%.The adsorption capacity of the raw diatomite on ciprofloxacin is better than that of the calcined diatomite. The SEM indicates that the pore size and pore quantity of the raw diatomite are both better than that of the calcined diatomite, which leads to the excellent adsorption capacity of the raw diatomite. The inhibition zone test exhibits that the diatomite based antibacterial inorganic material has good antibacterial activity and release properties. The inhibition zone diameters of the ciprofloxacin/diatomite inorganic materials are all above 20mm.
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