Abstract：Montmorillonite(MMT) was utilized to absorb three types of cationic photosensitizers, namely, meso-tetra(4-N-methylpyridyl)porphyrine tetratosylate (TMPyP), Zn(Ⅱ) meso-tetra (N-methyl-4-pyridyl) porphine tetrachloride (Zn-TMPyP) and methylene blue (MB), the as-obtained mixtures were then evenly dispersed in aqueous polyvinyl alcohol-styrylpyridine salt condensate (PVA-SbQ) solution, corresponding photoactive MMT/PS hydrogels were prepared by the assay of UV cross-linking eventually. Transmission electron microscopy (TEM) was employed to analyse morphology of MMT and one as-prepared MMT/PS hydrogel. Scanning electron microscopy (SEM) and thermogravimetric analysis (TGA) were applied to analyse the internal morphology and thermal properties of the as-prepared hydrogels. Finally, swelling properties and antibacterial effect against staphylococcus aureus (S. aureus) were investigated. The results show that three photoactive MMT/PS hydrogels are successfully prepared with good swelling properties. The as-prepared hydrogels exhibit inactivation against S. aureus to some extent, furthermore, the hydrogel which immobilizes Zn-TMPyP reveals best inactivation efficacy, with a sterilization rate of 98.49%.
 郑辉东,邱洪峰,郑玉婴,等. 负载纳米银EVA复合发泡材料的制备及其抗菌性能[J]. 材料工程,2016,44(7):107-112. ZHENG H D,QIU H F,ZHENG Y Y,et al. Preparation and antibacterial property of EVA composite foams supported by nano-silver[J]. Journal of Materials Engineering,2016,44(7):107-112.
 高党鸽,陈琛,吕斌,等. 原位制备季铵盐聚合物/纳米ZnO复合抗菌剂[J]. 材料工程,2015,43(6):38-45. GAO D G,CHEN C,LYU B,et al. Synthesis polymer quaternary ammonium salt/nano-ZnO composite antibacterial agent via in-situ method[J]. Journal of Materials Engineering,2015,43(6):38-45.
 吕生华,李莹,杨文强,等. 氧化石墨烯/壳聚糖生物复合材料的制备及应用研究进展[J]. 材料工程,2016,44(10):119-128. LYU S H,LI Y,YANG W Q,et al. Research progress on preparation and application of graphene oxide/chitosan biocomposites[J]. Journal of Materials Engineering,2016,44(10):119-128.
 WAINWRIGHT M. Photodynamic antimicrobial chemotherapy (PACT)[J]. J Antimicrob Chemother,1998,42(1):13-28.
 SPAGNUL C,TURNER L C,BOYLE R W. Immobilized photosensitizers for antimicrobial applications[J]. J Photochem Photobiol B-Biol,2015,150:11-30.
 SCHLACHET I,SOSNIK A. Protoporphyrin IX-modified chitosan-g-oligo (NiPAAm) polymeric micelles:from physical stabilization to permeability characterization in vitro[J]. Biomater Sci,2017,5(1):128-140.
 ALVES E,FAUSTINO M A F,NEVES M,et al. Potential applications of porphyrins in photodynamic inactivation beyond the medical scope[J]. J Photochem Photobiol C-Photochem Rev,2015,22:34-57.
 CAVALLARO A,TAHERI S,VASILEV K. Responsive and "smart" antibacterial surfaces:common approaches and new developments (review)[J]. Biointerphases,2014,9(2):10-19.
 BUJDAK J,KOMADEL P. Interaction of methylene blue with reduced charge montmorillonite[J]. J Phys Chem B,1997,101(44):9065-9068.
 BETTANIN F,FONTINELLES T A D,MACIEL C D,et al. Aggregation of photosensitizers:the role of dispersion and solvation on dimer formation energetics[J]. Theoretical Chemistry Accounts,2015,134(12):11-23.
 ZHANG H F,HUSSAIN I,BRUST M,et al. Aligned two-and three-dimensional structures by directional freezing of polymers and nanoparticles[J]. Nat Mater,2005,4(10):787-793.
 WU J,MEREDITH J C. Assembly of chitin nanofibers into porous biomimetic structures via freeze drying[J]. ACS Macro Lett,2014,3(2):185-190.
 CUI J,WANG Q,WEI Q. Synthesis and characterization of cross-linked SbQ/montmorillonite composites[J]. Polymer Materials Science & Engineering,2015,31(7):159-162.
 ROTOMSKIS R,STRECKYTE G,BAGDONAS S. Phototransformations of sensitizers 1. significance of the nature of the sensitizer in the photobleaching process and photoproduct formation in aqueous solution[J]. J Photochem Photobiol B-Biol,1997,39:167-171.
 HORVATH O,HUSZANK R,VALICSEK Z,et al. Photophysics and photochemistry of kinetically labile,water-soluble porphyrin complexes[J]. Coordination Chemistry Reviews,2006,250(13/14):1792-1803.
 许凤兰,李玉宝,李吉东,等. 纳米羟基磷灰石/聚乙烯醇复合水凝胶的溶胀性[J]. 材料工程,2005(7):15-18. XU F L,LI Y B,LI J D,et al.Swelling properties of nano-hydroxyaptite/polyvinyl alcohol hydrogel composite[J]. Journal of Materials Engineering,2005(7):15-18.
 崔晓彤,刘金龙,张德坤,等. 不同接触尺度下PVA/HA复合水凝胶的滑动摩擦行为[J]. 材料工程,2016,44(5):59-64. CUI X T,LIU J L,ZHANG D K,et al. Sliding friction behavior of PVA/HA composite hydrogels under different contacting scales[J]. Journal of Materials Engineering,2016,44(5):59-64.
 GOMEZ I,OTAZO E M,HERNANDEZ H,et al. Thermal degradation study of PVA derivative with pendant phenylthionecarbamate groups by DSC/TGA and GC/MS[J]. Polym Degrad Stabil,2015,112:132-136.
 XU J,BAI H Y,WANG M,et al. Properties of hyaluronan/PVA-SbQ composite films processed by casting[J]. Polymers & Polymer Composites,2013,21(1):55-60.
 REDMOND R W,GAMLIN J N. A compilation of singlet oxygen yields from biologically relevant molecules[J]. Photochem Photobiol,1999,70(4):391-475.
 ZHAO Z,LI Y,MENG S,et al. Susceptibility of methicillin-resistant staphylococcus aureus to photodynamic antimicrobial chemotherapy with α-d-galactopyranosyl zinc phthalocyanines:in vitro study[J]. Lasers in Medical Science,2014,29(3):1131-1138.