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材料工程  2019, Vol. 47 Issue (2): 56-61    DOI: 10.11868/j.issn.1001-4381.2017.000588
  研究论文 本期目录 | 过刊浏览 | 高级检索 |
阳离子光敏抗菌型水凝胶的制备及性能表征
董建成, 葛孝栋, 王清清, 魏取福
江南大学 生态纺织教育部重点实验室, 江苏 无锡 214122
Preparation and property characterization of cationic photoantimicrobial hydrogel
DONG Jian-cheng, GE Xiao-dong, WANG Qing-qing, WEI Qu-fu
Key Laboratory of Eco-textile(Ministry of Education), Jiangnan University, Wuxi 214122, Jiangsu, China
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摘要 利用蒙脱土(MMT)分别吸附3种阳离子光敏剂(meso-四(1-甲基吡啶嗡-4-基)卟吩对甲苯磺酸盐(TMPyP)、meso-四(N-甲基-4-吡啶)卟吩四氯化锌(Zn-TMPyP)、亚甲基蓝(MB)),然后均匀分散在聚乙烯醇-苯乙烯基吡啶盐缩合物(PVA-SbQ)的水溶液中,通过紫外光交联法制备出相应的光敏MMT/PS水凝胶。借助透射电子显微镜(TEM)对MMT和MMT/PS形貌结构进行分析,利用扫描电子显微镜(SEM)、热重分析仪(TGA)对3种光敏水凝胶的内部形貌、热学性能进行分析,研究其溶胀性能及对金黄色葡萄球菌的抗菌效果。结果表明:3种光敏MMT/PS水凝胶均具有良好的溶胀性能。抗菌结果显示,三者对金黄色葡萄球菌均具有一定的杀灭效果,其中负载Zn-TMPyP的水凝胶在光照条件下对金黄色葡萄球菌的杀菌率达到98.49%。
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董建成
葛孝栋
王清清
魏取福
关键词 蒙脱土水凝胶光敏抗菌金黄色葡萄球菌    
Abstract:Montmorillonite(MMT) was utilized to absorb three types of cationic photosensitizers, namely, meso-tetra(4-N-methylpyridyl)porphyrine tetratosylate (TMPyP), Zn(Ⅱ) meso-tetra (N-methyl-4-pyridyl) porphine tetrachloride (Zn-TMPyP) and methylene blue (MB), the as-obtained mixtures were then evenly dispersed in aqueous polyvinyl alcohol-styrylpyridine salt condensate (PVA-SbQ) solution, corresponding photoactive MMT/PS hydrogels were prepared by the assay of UV cross-linking eventually. Transmission electron microscopy (TEM) was employed to analyse morphology of MMT and one as-prepared MMT/PS hydrogel. Scanning electron microscopy (SEM) and thermogravimetric analysis (TGA) were applied to analyse the internal morphology and thermal properties of the as-prepared hydrogels. Finally, swelling properties and antibacterial effect against staphylococcus aureus (S. aureus) were investigated. The results show that three photoactive MMT/PS hydrogels are successfully prepared with good swelling properties. The as-prepared hydrogels exhibit inactivation against S. aureus to some extent, furthermore, the hydrogel which immobilizes Zn-TMPyP reveals best inactivation efficacy, with a sterilization rate of 98.49%.
Key wordsmontmorillonite    hydrogel    photodynamic antibacterial inactivation    staphylococcus aureus
收稿日期: 2017-05-08      出版日期: 2019-02-21
中图分类号:  TQ619.9  
通讯作者: 魏取福(1964-),男,教授,博士,从事功能纺织材料方面的研究工作,联系地址:江苏省无锡市江南大学生态纺织教育部重点实验室(214122),E-mail:qfwei@jiangnan.edu.cn     E-mail: qfwei@jiangnan.edu.cn
引用本文:   
董建成, 葛孝栋, 王清清, 魏取福. 阳离子光敏抗菌型水凝胶的制备及性能表征[J]. 材料工程, 2019, 47(2): 56-61.
DONG Jian-cheng, GE Xiao-dong, WANG Qing-qing, WEI Qu-fu. Preparation and property characterization of cationic photoantimicrobial hydrogel. Journal of Materials Engineering, 2019, 47(2): 56-61.
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http://jme.biam.ac.cn/CN/10.11868/j.issn.1001-4381.2017.000588      或      http://jme.biam.ac.cn/CN/Y2019/V47/I2/56
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