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材料工程  2018, Vol. 46 Issue (8): 14-26    DOI: 10.11868/j.issn.1001-4381.2017.001242
  综述 本期目录 | 过刊浏览 | 高级检索 |
丝素蛋白及其复合材料的研究进展
李莹莹1,2, 王昉1,2, 刘其春1,2, 张东敏1,2, 张雪1,2, 马青玉3, 顾正桂2
1. 南京师范大学 分析测试中心, 南京 210023;
2. 南京师范大学 化学与材料科学学院, 南京 210023;
3. 南京师范大学 物理科学与技术学院, 南京 210023
Research Progress in Silk Fibroin and Its Composite Materials
LI Ying-ying1,2, WANG Fang1,2, LIU Qi-chun1,2, ZHANG Dong-min1,2, ZHANG Xue1,2, MA Qing-yu3, GU Zheng-gui2
1. Center of Analysis and Testing, Nanjing Normal University, Nanjing 210023, China;
2. School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China;
3. School of Physics and Technology, Nanjing Normal University, Nanjing 210023, China
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摘要 丝素蛋白是天然高分子材料,具有很好的生物相容性、生物降解性等优良的性能,在医药、食品和美容等领域具有很好的发展前景。本文阐述了丝素蛋白及其分别与天然生物蛋白、无机物、合成聚合物、碳纳米管和氧化石墨烯进行复合的制备技术、材料结构、性能以及研究发展趋势,介绍了丝素蛋白及其复合材料的不同制备机制,分析了制备方法与结构和材料性能之间的关系及不同材料间的相互作用机理,总结了其在组织工程、药物释放和抗凝血性等方面的应用,并提出丝素蛋白复合材料实现规模化生产、发展智能材料以及从基因层面对丝素蛋白进行重组改性方面的未来发展趋势。
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李莹莹
王昉
刘其春
张东敏
张雪
马青玉
顾正桂
关键词 丝素蛋白复合材料结构性能制备方法进展    
Abstract:Silk fibroin is a natural polymer with biocompatibility,biodegradability and other excellent properties, which is a promising material in the fields of medicine,food and cosmetics,etc. In this work,the preparation techniques,material structure,properties and development trend for silk fibroin and its composites with natural biological protein,inorganic material,synthetic polymer,carbon nanotube and graphene oxide were introduced, respectively. The preparation principles of materials were explained,with an emphasis on the relationship between preparation methods and properties. The interaction mechanism between individual composites was analyzed,and the application on tissue engineering,drug application,anticoagulant materials and other aspects were also summarized. According to the key factors which restrict the research and development of silk fibroin and its composites,the promising future development ways were proposed,for example,realizing the scale production, developing the intelligent materials and restructuring modification of silk fibroin from the gene aspect.
Key wordssilk fibroin(SF)    composite material    structure and property    preparation method    development
收稿日期: 2017-09-30      出版日期: 2018-08-17
中图分类号:  TB324  
通讯作者: 王昉(1966-),女,副教授,硕导,主要从事高分子及其复合材料的制备、表征、应用以及仪器分析研究工作,联系地址:江苏省南京市文苑路1号南京师范大学分析测试中心(210023),E-mail:wangfang@njnu.edu.cn     E-mail: wangfang@njnu.edu.cn;guzhenggui@njnu.edu.cn
引用本文:   
李莹莹, 王昉, 刘其春, 张东敏, 张雪, 马青玉, 顾正桂. 丝素蛋白及其复合材料的研究进展[J]. 材料工程, 2018, 46(8): 14-26.
LI Ying-ying, WANG Fang, LIU Qi-chun, ZHANG Dong-min, ZHANG Xue, MA Qing-yu, GU Zheng-gui. Research Progress in Silk Fibroin and Its Composite Materials. Journal of Materials Engineering, 2018, 46(8): 14-26.
链接本文:  
http://jme.biam.ac.cn/CN/10.11868/j.issn.1001-4381.2017.001242      或      http://jme.biam.ac.cn/CN/Y2018/V46/I8/14
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