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材料工程  2014, Vol. 0 Issue (6): 62-67    DOI: 10.11868/j.issn.1001-4381.2014.06.012
  材料与工艺 本期目录 | 过刊浏览 | 高级检索 |
不同高温处理工艺对C/C复合材料生物相容性的影响
倪昕晔1,2,3, 李爱军1, 钟萍2, 林涛2, 熊信柏4, 顾卫东2
1. 上海大学 材料科学与工程学院, 上海 200444;
2. 南京医科大学 附属常州第二人民医院, 江苏 常州 213003;
3. 南京航空航天大学 材料科学与技术学院, 南京 210016;
4. 深圳大学 材料学院, 广东 深圳 518060
Effect of Different High Temperature Treatment Processes on Biocompatibility of Carbon/Carbon Composites
NI Xin-ye1,2,3, LI Ai-jun1, ZHONG Ping2, LIN Tao2, XIONG Xin-bo4, GU Wei-dong2
1. School of Materials Science and Engineering, Shanghai University, Shanghai 200444, China;
2. Second People's Hospital of Changzhou, Nanjing Medical University, Changzhou 213003, Jiangsu, China;
3. College of Material Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China;
4. College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, Guangdong, China
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摘要 对比研究了经不同时间高温石墨化处理后的C/C复合材料有毒物质含量及材料对成骨细胞生长的影响。结果表明,延长高温处理时间可以去除有毒物质As,Pb和减少有毒Hg,Cd,Al等含量。经过较短时间(4,8h)处理后的C/C复合材料表面成骨细胞生长缓慢,有明显的毒性作用,而超过较长时间(12,16h)处理后的C/C复合材料表面成骨细胞生长良好。延长C/C复合材料高温处理时间可以提高其生物相容性。
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倪昕晔
李爱军
钟萍
林涛
熊信柏
顾卫东
关键词 C/C复合材料高温处理生物相容性    
Abstract:The effect of the toxic substances of carbon/carbon composites by different graphitization treatment times and their impact on osteoblast growth was studied. The results show that prolonging heat treatment can remove toxic substances As and Pb, and reduce Hg, Cd, Al, and other toxic contents. In addition, osteoblasts slowly grow by short time(4,8h) high-temperature treatment and show an obvious toxic effect, but osteoblasts grow well on the carbon/carbon composite surface by long time(12,16h) high-temperature treatment.Thus, extended heat treatment can significantly improve the biocompatibility of the carbon/carbon composites.
Key wordscarbon/carbon composite    high temperature treatment    biocompatibility
收稿日期: 2012-12-18      出版日期: 2014-06-20
中图分类号:  TB332  
基金资助:国家自然科学基金项目(51172147);江苏省常州市社会发展项目(CJ20130019);南京医科大学校基金重点项目(2011NJMU226)
通讯作者: 顾卫东(1968- ),男,主任医师,主要从事生物材料的临床应用,联系地址:常州市兴隆巷29号,南京医科大学附属常州第二人民医院(213003),E-mail:nxy1975@aliyun.com     E-mail: nxy1975@aliyun.com
作者简介: 倪昕晔(1975- ),男,博士,高级工程师,主要从事生物材料的制备和临床应用,联系地址:常州市兴隆巷29号,南京医科大学附属常州第二人民医院(213003),E-mail:nxy2000@aliyun.com
引用本文:   
倪昕晔, 李爱军, 钟萍, 林涛, 熊信柏, 顾卫东. 不同高温处理工艺对C/C复合材料生物相容性的影响[J]. 材料工程, 2014, 0(6): 62-67.
NI Xin-ye, LI Ai-jun, ZHONG Ping, LIN Tao, XIONG Xin-bo, GU Wei-dong. Effect of Different High Temperature Treatment Processes on Biocompatibility of Carbon/Carbon Composites. Journal of Materials Engineering, 2014, 0(6): 62-67.
链接本文:  
http://jme.biam.ac.cn/CN/10.11868/j.issn.1001-4381.2014.06.012      或      http://jme.biam.ac.cn/CN/Y2014/V0/I6/62
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